@julian said:
Correct, AdSense doesn't work so well with single page apps because it cannot properly detect page changes and disables ads after the we change pages three times.
Have you considered using DoubleClick for publishers?
I do not know anything about DoubleClick 
Widget:
<div id='div-gpt-ad-xxxxxxxxxxx'>
<script type='text/javascript'>
googletag.cmd.push(function() { googletag.display('div-gpt-ad-xxxxxxxxxxxxxx); });
</script>
</div>
<br>
</center>
head code:
<script type='text/javascript'>
var googletag = googletag || {};
googletag.cmd = googletag.cmd || [];
(function() {
var gads = document.createElement('script');
gads.async = true;
gads.type = 'text/javascript';
var useSSL = 'https:' == document.location.protocol;
gads.src = (useSSL ? 'https:' : 'http:') +
'//www.googletagservices.com/tag/js/gpt.js';
var node = document.getElementsByTagName('script')[0];
node.parentNode.insertBefore(gads, node);
})();
</script>
<script type='text/javascript'>
googletag.cmd.push(function() {
var mappingLeaderboard = googletag.sizeMapping().
addSize([1024, 768 ], [728, 90]).
addSize([500, 500 ], [468, 60]).
addSize([1, 1 ], [320, 50]).
build();
googletag.defineSlot('/xx/xx', [[320, 50], [468, 60], [728, 90]], 'div-gpt-ad-xxxxxx').defineSizeMapping(mappingLeaderboard).addService(googletag.pubads());
googletag.pubads().enableSingleRequest();
googletag.enableServices();
});
</script>
