Not really, it would require essentially making a new theme to incorporate the different styles.
Turn off Skin in Persona Theme
How to turn off user choose skin in Persona Theme?
You can hide the option via custom CSS. I'd like to remove it eventually for good, although lots of people still use skins
@paopevil Go to ACP -> Settings -> User and enable the option "Prevent users from choosing a custom skin".
@pichalite Thank you! This working!